Kratom, better known as Mitragyna Speciosa in the scientific community, is a raw botanical that comes from the Rubiaceae family of trees. A cousin of the coffee tree, Kratom is native to the tropical rainforests of Malaysia, Thailand and Indonesia. Mitragyna Speciosa powder and leaves have been used for centuries in customary rituals, ceremonies, and folk medicine all over Southeast Asia, and it has only gained popularity in the western world during recent years. Although Kratom is widely sold as a raw botanical product for various uses, in both crushed leaf and powder form, it has not been approved for human consumption by the Food and Drug Administration (FDA).
As a recreational drug, the leaves are chewed or drank as a tea to elevate mood (as a euphoriant) and enhance physical endurance.
As a medicine, kratom is used for anxiety, cough, depression, diabetes, diarrhea, high blood pressure, pain, to improve sexual performance, and to lessen symptoms of opiate withdrawal.
Medications changed by the liver (Cytochrome P450 2C19 (CYP2C19) substrates)Interaction Rating: Moderate Be cautious with this combination.Talk with your health provider.
Some medications are changed and broken down by the liver. Kratom might decrease how quickly the liver breaks down some medications. Taking kratom with these medications that are changed by the liver might increase the effects and side effects of these medications. Before taking kratom, talk to your healthcare provider if you take any medications that are changed by the liver.
Some of these medications that are changed by the liver include amitriptyline (Elavil), carisoprodol (Soma), citalopram (Celexa), diazepam (Valium), lansoprazole (Prevacid), omeprazole (Prilosec), phenytoin (Dilantin), warfarin (Coumadin), and many others.
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